| Datum | Beginn | Begegnung | Abfahrt | Rückfahrt |
| 17.08.2018 (Fr) | 20:00 | FC Twente – Sparta | 18:30 | 22:45 |
| 31.08.2018 (Fr) | 20:00 | FC Twente – Roda JC | 18:30 | 22:45 |
| 08.09.2018 (Sa) | 18:30 | FC Twente – TOP Oss | 17:00 | 21:15 |
| 30.09.2018 (So) | 14:30 | FC Twente – Jong PSV | 13:00 | 17:15 |
| 14.10.2018 (So) | 16:45 | FC Twente – MVV | 15:15 | 19:30 |
| 26.10.2018 (Fr) | 20:00 | FC Twente – Almere City FC | 18:30 | 22:45 |
| 02.11.2018 (Fr) | 20:00 | FC Twente – RKC Waalwijk | 18:30 | 22:45 |
| 18.11.2018 (So) | 14:30 | FC Twente – Go Ahead Eagles | 13:00 | 17:15 |
| 30.11.2018 (Fr) | 20:00 | FC Twente – Jong Ajax | 18:30 | 22:45 |
| 21.12.2018 (Fr) | 20:00 | FC Twente – NEC | 18:30 | 22:45 |
| 18.01.2019 (Fr) | 20:00 | FC Twente – Jong FC Utrecht | 18:30 | 22:45 |
| 01.02.2019 (Fr) | 20:00 | FC Twente – Helmond Sport | 18:30 | 22:45 |
| 22.02.2019 (Fr) | 20:00 | FC Twente – FC Eindhoven | 18:30 | 22:45 |
| 15.03.2019 (Fr) | 20:00 | FC Twente – FC Volendam | 18:30 | 22:45 |
| 29.03.2019 (Fr) | 20:00 | FC Twente – FC Den Bosch | 18:30 | 22:45 |
| 05.04.2019 (Fr) | 20:00 | FC Twente – FC Dordrecht | 18:30 | 22:45 |
| 12.04.2019 (Fr) | 20:00 | FC Twente – Telstar | 18:30 | 22:45 |
| 22.04.2019 (Mo) | 14:30 | FC Twente – Jong AZ | 13:00 | 17:15 |
| 03.05.2019 (Fr) | 20:00 | FC Twente – Cambuur | 18:30 | 22:45 |
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